Tylox Drug Interactions

A number of medications, including antidepressants, benzodiazepines, and barbiturates, may cause drug interactions with Tylox. These interactions could increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. To help prevent these potentially serious Tylox interactions, be sure to tell your healthcare provider about all other medications you are taking before using the pain reliever.

Tylox Interactions: An Overview

Tylox® (oxycodone/APAP) can potentially interact with a number of other medications. Some of the medicines that may lead to Tylox drug interactions include:
  • Alcohol
  • Anticholinergic medications, including (but not limited to):




    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)


  • Benzodiazepines, such as:





  • Sleep medications.
What Your Pharmacist Wishes You Knew About Chronic Pain Medications

Tylox Medication Information

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