Drug Interactions With Tapentadol

Alcohol, antipsychotic medications, and tramadol are just a few of the products that can react with tapentadol. Drug interactions with this pain reliever can be dangerous, due to the risk of serotonin syndrome (a group of symptoms including confusion, fast heartbeat, and difficulty walking). To help reduce your risk, tell your healthcare provider about any other medications you are taking while on tapentadol.

An Overview of Tapentadol Interactions

Tapentadol (Nucynta™) can potentially interact with a number of other medications. Some of the medicines that may lead to drug interactions with tapentadol include but are not limited to:
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Tapentadol Drug Information

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