Roxicet Side Effects

Common side effects of Roxicet include drowsiness, nausea, and constipation. While these side effects generally require little or no treatment, potentially serious side effects are possible while taking this medication. If you experience more serious Roxicet side effects, such as difficulty passing urine, severe constipation, or slow or irregular breathing, notify your healthcare provider right away.

An Introduction to Roxicet Side Effects

As with any medicine, Roxicet™ (oxycodone/APAP) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with Roxicet. Your healthcare provider can discuss a more complete list of Roxicet side effects with you.)
 

Common Side Effects of Roxicet

Roxicet is an older medication, approved before the Food and Drug Administration (FDA) required manufacturers to include detailed information about side effects in the prescribing information for medications. Therefore, only vague information is available about the possible side effects of Roxicet; no specific percentages for the individual side effects are provided.
 
Based on this information, common side effects of Roxicet include:
 
  • Nausea, with or without vomiting
  • Constipation (see Roxicet and Constipation)
  • Dizziness or lightheadedness
  • Drowsiness
  • An unexplained, pleasant feeling (euphoria) or unpleasant feeling (dysphoria)
  • Itching.
     
People also often assume that itching indicates an allergic reaction. However, itching is not always a sign of an allergy to Roxicet, especially if no other allergy symptoms occur. Opiates (such as the one in Roxicet) cause a release of histamine, which often causes itching unrelated to any allergy.
 
Many people consider themselves "allergic" to Roxicet if they experience nausea and vomiting while taking it. However, this is a common side effect and does not indicate a true allergy. In many cases, this side effect goes away as a person continues to use Roxicet. Taking this medication with food may help reduce the risk of nausea and vomiting.
 
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