Precautions and Warnings With Propoxyphene/Acetaminophen

If you are about to take propoxyphene/acetaminophen, it's important to know the precautions and warnings with this drug. For example, this medication isn't right for everyone. Since propoxyphene/acetaminophen contains a narcotic and has the potential to be abused, it is not recommended for people who have a history of alcohol or drug dependence. An accidental or intentional overdose can be fatal within 15 minutes.

What Should I Tell My Healthcare Provider Before Taking Propoxyphene/Acetaminophen?

You should talk with your healthcare provider prior to taking propoxyphene/acetaminophen (Darvocet®) if you have:
 
  • A lung problem, such as chronic obstructive pulmonary disease (COPD) or cor pulmonale
  • Problems with your pancreas or gallbladder
  • A history of head injury
  • An intestinal blockage (bowel obstruction)
  • Depression
  • Suicidal tendencies
  • Liver disease, such as cirrhosis, liver failure, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • A history of drug or alcohol dependence
  • Any allergies, including allergies to foods, dyes, or preservatives.
      
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
     
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 

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(Precautions and Warnings With Propoxyphene/Acetaminophen Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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