Oxycodone and Pregnancy

In animal studies on pregnancy and oxycodone, the medication did not seem to increase the risk of birth defects or other problems. Limited human studies have also shown that oxycodone does not appear to cause birth defects. However, as a narcotic, oxycodone can cause withdrawal symptoms in the infant after delivery. If you are taking this medication and pregnancy occurs, talk to your healthcare provider.

Is Oxycodone Safe During Pregnancy?

Oxycodone hydrochloride is an active ingredient used in many prescription pain medications. It is a narcotic, opioid (morphine-like) medication. Animal studies indicate that oxycodone is unlikely to cause birth defects.
It is important to note that oxycodone is available by itself or in combination with one or more other active ingredients. The other active ingredients (which vary, depending on the particular product) may have other pregnancy Category ratings and may cause other problems when used during pregnancy.

Pregnancy Category B

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been adequately studied in pregnant humans, but do not appear to cause harm to the fetus in animal studies. Medications that have been shown to be safe for use in pregnancy in humans (but have caused problems in laboratory animals) are also given a Category B rating.
When given to pregnant animals, oxycodone did not seem to increase the risk of birth defects or other problems. Very limited human studies also suggest that oxycodone does not seem to cause birth defects in humans. However, oxycodone is a narcotic, and using this drug during the end of a pregnancy may cause narcotic withdrawal in the infant after delivery. Such withdrawal symptoms may include:
  • Hyperactive reflexes
  • Fast breathing
  • Increased stools
  • Irritability and excessive crying
  • Shakiness (tremors)
  • Sneezing
  • Yawning
  • Vomiting
  • Fever.
Oxycodone is not recommended for pain control during labor or delivery, as it may cause breathing problems in the newborn.
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Oxycodone HCL Medication Information

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