Propoxyphene/acetaminophen is a prescription medicine licensed for the treatment of mild to moderate pain. It is a combination product that contains a narcotic and a pain reliever commonly found in over-the-counter drugs. The medication comes in tablet form and is taken every four hours as needed for pain. It is classified as a controlled substance and has the potential to be abused.
What Is Propoxyphene/Acetaminophen?
In November 2010, the United States Food and Drug Administration (FDA) withdrew all medications that contain propoxyphene from the market. It has been determined that the risks of propoxyphene outweigh the possible benefits. In particular, the FDA was concerned about the drug's ability to cause serious changes in the heart rhythm, even at normal doses. Pharmacies will no longer sell this medication, and people who take it should stop and ask their healthcare provider for a more suitable pain medication.
Propoxyphene/acetaminophen (Darvocet®) is a prescription medication approved to treat mild-to-moderate pain, with or without a fever. It contains two different medications -- propoxyphene napsylate (Darvon-N®) and acetaminophen (Tylenol®). There are actually three different types of propoxyphene/acetaminophen, including:
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed December 24, 2008.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins; 2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed date.
Food and Drug Administration, Center for Drug Evaluation and Research. Propoxyphene: Withdrawal -- Risk of Cardiac Toxicity (11/19/2010). FDA Web site. Available at: http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm234389.htm. November 19, 2010.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind.
Site users seeking medical advice about their specific situation should consult with their own physician. Click