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Potential Side Effects

As with any medicine, propoxyphene/acetaminophen can cause side effects. However, not everyone who takes the drug will have problems. Most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
Common side effects of propoxyphene/acetaminophen include, but are not limited to:
  • Dizziness
  • Drowsiness
  • Nausea
  • Vomiting.
(Click Side Effects of Propoxyphene/Acetaminophen to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)

What Should I Tell My Healthcare Provider Before Taking Propoxyphene/Acetaminophen?

You should talk with your healthcare provider prior to taking this medication if you have:
  • A lung problem, such as chronic obstructive pulmonary disease (COPD) or cor pulmonale
  • Problems with your pancreas or gallbladder
  • A history of head injury
  • An intestinal blockage (bowel obstruction)
  • Depression
  • Suicidal tendencies
  • Liver disease, such as cirrhosis, liver failure, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • A history of drug or alcohol dependence
  • Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Propoxyphene/Acetaminophen to learn more, including information on who should not take the drug.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
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