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Although most people do not experience any problems while taking Flexeril, it is possible for side effects to occur. Clinical trials have shown that the most common side effects include drowsiness, dry mouth, and dizziness. In most cases, these problems are easily treated. However, you should contact your healthcare provider if you develop any potentially serious side effects of Flexeril, such as fainting, an explained rash, or difficulty passing urine.

An Introduction to Flexeril Side Effects

As with any medicine, side effects are possible with Flexeril® (cyclobenzaprine hydrochloride). However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with Flexeril. Your healthcare provider can discuss a more complete list of Flexeril side effects with you.)
 

Common Side Effects of Flexeril

Flexeril has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to the side effects that occurred in another group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group not taking the medicine.
 
In these studies, the most common side effects with Flexeril included:
 
  • Drowsiness -- in up to 39 percent of people
  • Dry mouth -- up to 32 percent (see Flexeril and Dry Mouth)
  • Dizziness -- up to 11 percent.
     
Other common side effects (occurring in 1 to 3 percent of people) included:
 
  • Fatigue or tiredness
  • Weakness
  • Nausea
  • Constipation
  • Indigestion or heartburn
  • Unpleasant taste
  • Blurred vision
  • Nervousness
  • Confusion.
     
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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