Drug Interactions With Ketorolac Nasal Spray

Before using ketorolac nasal spray, make sure your healthcare provider is aware of any other medications you are taking (including nonprescription medicines and herbal supplements). Some products, such as St. John's wort, seizure medications, and muscle relaxants, can cause negative drug interactions when taken with ketorolac nasal spray. These reactions can potentially cause side effects or decrease the effectiveness of the drugs.

An Overview of Ketorolac Nasal Spray Interactions

Ketorolac nasal spray (Sprix™) may potentially interact with a number of other medications. Some of the drugs that may lead to interactions with this nasal spray include but are not limited to:
 
 
  • Angiotensin II receptor blockers (ARBs), such as:

 

  
  • Corticosteroids, including (but not limited to):
     
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
 
 
 
 
 
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
 
 
 
 
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Ketorolac Nasal Spray Drug Information

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