Kadian Side Effects

Serious Side Effects Seen With Kadian

Some side effects with Kadian, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include, but are not limited to:
  • The urge to take more Kadian than prescribed or for a non-medical purpose (see Kadian Abuse)
  • Confusion
  • Severe constipation
  • Falling or unsteadiness
  • Slow or irregular breathing
  • A slow heart rate (bradycardia)
  • Difficulty passing urine
  • Low blood pressure (hypotension)
  • Severe drowsiness
  • Seizures
  • Unusual changes in mood or behavior
  • Signs of an allergic reaction, such as:


    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.


It should be noted that many people develop itching due to morphine (the active ingredient in Kadian) but are not allergic to the medication. Morphine causes a release of histamine, resulting in itching unrelated to any allergy. If you develop itching but no other allergy symptoms, it is unlikely that you are allergic to Kadian. Tell your healthcare provider, though, since there are medications available to help relieve the itching.

Less Common Kadian Side Effects

There are other, less common Kadian side effects that can occur. These side effects occur in less than 3 percent of people taking the medication. For these side effects, it is difficult to tell whether they are actually caused by Kadian or something else.
These less common side effects include, but are not limited to:
  • Weakness
  • Accidental injury
  • Fever
  • Headaches
  • Sweating
  • Chills
  • Back pain
  • Facial flushing
  • Dry mouth
  • Abnormal dreams
  • Insomnia
  • A spinning sensation (vertigo)
  • Blurred vision
  • Difficulty urinating
  • Decreased sex drive.
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Kadian Medication Information

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