Flexeril Drug Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Flexeril is combined with any of the drugs listed above.
Alcohol
Combining alcohol with Flexeril can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. It is best to avoid alcohol while taking Flexeril.
Anesthetics
Combining anesthetics with Flexeril can increase your risk of side effects (especially drowsiness, confusion, memory loss, or difficulty breathing), and serious side effects may occur. Make sure your healthcare providers know you are taking Flexeril before you undergo any surgical procedure.
Anticholinergic Medications
Taking Flexeril with an anticholinergic medication may increase your risk of a dry mouth, blurred vision, difficulty passing urine, or other problems. Check with your healthcare provider before taking Flexeril with an anticholinergic medication.
Barbiturates
Taking a barbiturate with Flexeril can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Make sure to talk to your healthcare provider before taking Flexeril with a barbiturate.
Benzodiazepines
Combining Flexeril with a benzodiazepine can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Make sure to talk to your healthcare provider before taking Flexeril with a benzodiazepine.
Monoamine Oxidase Inhibitors (MAOIs)
Do not take Flexeril and a MAOI together (or within two weeks of each other), as combining these medications can cause life-threatening problems.
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