Flexeril Interactions

Flexeril Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Flexeril is combined with any of the drugs listed above.
 
Alcohol
Combining alcohol with Flexeril can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. It is best to avoid alcohol while taking Flexeril.
 
Anesthetics
Combining anesthetics with Flexeril can increase your risk of side effects (especially drowsiness, confusion, memory loss, or difficulty breathing), and serious side effects may occur. Make sure your healthcare providers know you are taking Flexeril before you undergo any surgical procedure.
 
Anticholinergic Medications
Taking Flexeril with an anticholinergic medication may increase your risk of a dry mouth, blurred vision, difficulty passing urine, or other problems. Check with your healthcare provider before taking Flexeril with an anticholinergic medication.
 
Barbiturates
Taking a barbiturate with Flexeril can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Make sure to talk to your healthcare provider before taking Flexeril with a barbiturate.
 
Benzodiazepines
Combining Flexeril with a benzodiazepine can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may also occur. Make sure to talk to your healthcare provider before taking Flexeril with a benzodiazepine.
 
Certain Antidepressants or Fibromyalgia Medications
Taking Flexeril with certain depression or fibromyalgia medications can cause a group of symptoms called serotonin syndrome. These symptoms include:
  • Confusion
  • Hallucination
  • Fast heartbeat
  • Feeling faint
  • Fever
  • Sweating
  • Muscle spasm
  • Difficulty walking
  • Diarrhea.
 
Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be very dangerous.
 
Meperidine
Taking meperidine and Flexeril together may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
Alternative Treatments for Fibromyalgia

Flexeril Drug Information

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