Endocet Side Effects

Constipation, dizziness, and nausea are some of the common side effects that have been reported with Endocet. Side effects of the medication tend to be minor and are generally easy to treat, but some are potentially serious and may require immediate medical attention. Notify your healthcare provider if you experience severe drowsiness, difficulty passing urine, or slow or irregular breathing.

An Introduction to Endocet Side Effects

Just like any medicine, Endocet® (oxycodone/APAP) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Endocet. Your healthcare provider can discuss a more complete list of Endocet side effects with you.)

Common Side Effects of Endocet

Endocet was approved before the U.S. Food and Drug Administration (FDA) required manufacturers to include detailed information about side effects in the prescribing information for medications. Therefore, only vague information is available about Endocet side effects; no specific percentages for the individual side effects are provided.
Based on this limited information, common side effects may include:
  • Nausea, with or without vomiting
  • Constipation
  • Dizziness or lightheadedness
  • Drowsiness
  • An unexplained, pleasant feeling (euphoria) or unpleasant feeling (dysphoria)
  • Itching.
Many people consider themselves "allergic" to Endocet if they experience nausea and vomiting while taking it. However, this is a common side effect and does not indicate a true allergy. In many cases, this side effect goes away as a person continues to use Endocet. Taking the medication with food may help reduce the risk of nausea and vomiting.
People also often assume that itching indicates an allergic reaction. However, itching is not always a sign of an allergy to Endocet, especially if no other allergy symptoms occur. Opioids (such as the one in Endocet) cause a release of histamine, leading to itching unrelated to any allergy.
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