Amrix and Dry Mouth

Many side effects are possible with Amrix (cyclobenzaprine ER), and dry mouth appears to be one of them. In a clinical study, up to 14 percent of people taking the muscle relaxant reported having a dry mouth. If you are taking Amrix and dry mouth develops, talk to your healthcare provider so he or she can recommend treatment, adjust your dosage, or prescribe another medication.

Does Amrix Cause a Dry Mouth?

Dry mouth is the most common side effect of Amrix® (cyclobenzaprine ER). In one clinical study, up to 14 percent of people taking Amrix reported having a dry mouth, compared to just 2 percent of people taking a placebo (a "sugar pill" with no active ingredient). People taking a higher dose of Amrix were more likely to develop a dry mouth, compared to people taking a lower dose.

Suggestions for Amrix and Dry Mouth

Many medications (including Amrix) can cause a dry mouth. However, most people can deal with this side effect with a few simple suggestions. Some of these suggestions include:
  • Be aware of spicy or salty foods, as these foods may cause pain in a dry mouth.
  • Sip water or sugarless drinks often, especially during meals. This will make chewing and swallowing easier; it may also improve the taste of food.
  • Avoid drinks with caffeine, such as coffee, tea, and many sodas. Caffeine can dry out the mouth.
  • Avoid tobacco or alcohol, because these substances dry out the mouth.
  • Consider using a humidifier at night.
  • Chew sugarless gum or suck on sugarless, hard candy to stimulate saliva flow; cinnamon- or mint-flavored candies are good choices.
Sometimes a dry mouth can be more than just a bothersome side effect. A severely dry mouth can cause dental problems (since a dry mouth increases the risk of infections and decay). If you have tried these suggestions and still have a dry mouth, please contact your healthcare provider (or your dentist).
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